Post-nano strategies for drug delivery: multistage porous silicon microvectors

Microfluidic assembly of multistage porous silicon-lipid vesicles for controlled drug release.

A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi-lipid vesicle. This composite system...

Pluronic as nano-carier for drug delivery systems

A common approach for building a drug delivery system is to incorporate the drug within the nanocarrier that results in increased solubility, metabolic stability, and improved circulation time. However, recent developments indicate that selection of polymer nanomaterials can implement more than only inert carrier functions by being biological response modifiers. One representative of such mater...

Inhaled nano- and microparticles for drug delivery

The 21st century has seen a paradigm shift to inhaled therapy, for both systemic and local drug delivery, due to the lung's favourable properties of a large surface area and high permeability. Pulmonary drug delivery possesses many advantages, including non-invasive route of administration, low metabolic activity, control environment for systemic absorption and avoids first bypass metabolism. H...

Patent Profiling for Nano Enabled Drug Delivery

Nano Enabled Drug Delivery (NEDD) systems are rapidly emerging as a key sub-area of nanotechnology’s application. Drug Delivery Systems (DDS) can improve the administration and efficacy of pharmaceutical compounds including antibodies, peptides, vaccines, drugs and enzymes [1]. As one subset of drug delivery innovation, NEDD, in which the small molecule delivery systems are at the submicron sca...

Spray Freeze Dried Large Porous Particles for Nano Drug Delivery by Inhalation